Cyclic adenosine monophosphate – the second messenger of life information transmission

At the beginning of the 20th century, scientists have confirmed that the regulation between cells and cells is accomplished by transporting extracellular small molecular information substances from va

Cyclic adenosine monophosphate - the second messenger of life information transmission

At the beginning of the 20th century, scientists have confirmed that the regulation between cells and cells is accomplished by transporting extracellular small molecular information substances from various body fluids such as blood and lymph. Therefore, various body fluids such as blood and lymph are called the “first messenger” of human life information transmission. For example, the kidney cells secrete kidney hormones, etc., and the hormones are transported to the corresponding cells by blood, lymph, and the like. However, scientists later discovered that the original “first messenger” is not directly involved in the material and energy metabolism of cells. For example, hormones do not directly act on cells, but only transmit information to cells through hormones. The second messenger, which regulates the physiological activities and metabolism of the cells.

What is cyclic adenosine monophosphate?

Cyclic adenosine monophosphate - the second messenger of life information transmission

Cyclic adenosine monophosphate (cAMP) is an important substance involved in regulating the metabolism and biological functions of cells. It is the “second messenger” of life information transmission. It is a physiological activity that directly regulates cells in the human body and An important substance for metabolism

So, what effect does cyclic adenosine monophosphate have on cells in various parts of the body

cyclic adenosine monophosphate improves cardiovascular function

The occurrence of cardiovascular disease is closely related to the decrease of intracellular cyclic adenosine monophosphate content. In addition to cyclic adenosine monophosphate, cyclic adenosine monophosphate is involved in regulating substance metabolism, thereby enhancing myocardial contractility, increasing cardiac output, improving myocardial hypoxia, and dilating coronary arteries.It is mainly used for the treatment of cardiac insufficiency, angina pectoris and myocardial infarction。

Cyclic adenosine monophosphate - the second messenger of life information transmission

2、cyclic adenosine monophosphate anti-tumor

In 1992, Professor Miyazaki found that the decrease of intracellular cyclic adenosine monophosphate was the direct cause of malignant transformation of cells, but supplementation with cyclic adenosine monophosphate inhibited cell proliferation and transformed it into normal direction. Studies have found that cyclic adenosine monophosphate has a direct or indirect killing effect on tumor cells。

Cyclic adenosine monophosphate - the second messenger of life information transmission

3、cyclic adenosine monophosphate prevents brain cells from aging

Professor Eric Kandel’s research concluded that supplementation with cyclic adenosine monophosphate can repair brain cells, activate brain cells, convert short-term memory into long-term memory and delay the aging of brain cells.Therefore, Kandel was awarded the 2000 Nobel Prize in Physiology/Medical。

Cyclic adenosine monophosphate - the second messenger of life information transmission

4、cyclic adenosine monophosphate enhances the body’s immunity

Immunity is the physiological response of the human body to recognize and eliminate “dissidents.”The human immune system can not function properly, and it is very prone to infections such as bacteria and illness.Hyperimmune system can cause allergies, manifested in diseases: allergic dermatitis, measles, asthma, intractable headache, toothache, pink eye, acne, constipation and high blood pressure, high blood fat, heart disease, stroke and other cardiovascular diseases disease。

The study found that the levels of cyclic adenosine monophosphate and cyclic guanosine monophosphate in spleen lymphocytes of aged rats were significantly lower than those of young rats.Cyclic adenosine monophosphate has a selective inhibitory effect on the immune response of the body, inhibits the proliferation and function of immune-related cells (t cells, b cells and other macrophages), and can reduce the immune response of antibodies.By selectively inhibiting immune cells in the body, it can improve immune disorders such as atopic dermatitis, measles and asthma。

5、cyclic adenosine monophosphate can enhance the body hematopoietic function

Clinical trials have found that cyclic adenosine has a metabolic promoting effect on hematopoietic stem cells. By supplementing cyclic adenosine monophosphate, it can stimulate the hematopoietic function of bone marrow stem cells and thus effectively ameliorate and treat aplastic anemia。

Cyclic adenosine monophosphate - the second messenger of life information transmission

6、There are many other effects on cyclic adenosine monophosphate

For example, cyclic adenosine monophosphate protects liver function, cyclic adenosine monophosphate improves blood circulation, makes blood and blood fill, and cyclic adenosine monophosphate improves sleep, and cyclic adenosine monophosphate helps to get rid of skin diseases。

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